Hypertension 2015 65 (2): 440–446.Ĭappuccio FP, Elliott P, Allender PS, Pryer J, Follman DA, Cutler JA. Effectiveness of a tailored behavioral intervention to improve hypertension control: primary outcomes of a randomized controlled trial. J Clin Hypertens (Greenwich) 2012 14 (11): 767–772.įriedberg JP, Rodriguez MA, Watsula ME, Lin I, Wylie-Rosett J, Allegrante JP et al. Lifestyle educational program strongly increases compliance to nonpharmacologic intervention in hypertensive patients: a 2-year follow-up study. Hypertension 2003 42 (5): 878–884.įerrara AL, Pacioni D, Di Fronzo V, Russo BF, Staiano L, Speranza E et al. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Sugar and artificially sweetened soda consumption linked to hypertension: a systematic review and meta-analysis. J Hypertens 2014 32 (5): 990–996.Ĭheungpasitporn W, Thongprayoon C, Edmonds PJ, Srivali N, Ungprasert P, Kittanamongkolchai W et al. The role of body weight, fat distribution and weight change in ethnic differences in the 9-year incidence of hypertension. Grootveld LR, Van Valkengoed IG, Peters RJ, Ujcic-Voortman JK, Brewster LM, Stronks K et al. Sedentary behaviors and the risk of incident hypertension: the SUN Cohort. Lancet 2005 365 (9455): 217–223.īeunza JJ, Martínez-González MA, Ebrahim S, Bes-Rastrollo M, Núñez J, Martínez JA et al. Global burden of hypertension: analysis of worldwide data. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Further high-quality research is still warranted to confirm the magnitude of the effect of CaD supplementation on the changes of BP among participants with different ethnicity, gender, health status and CaD supplements. Subgroup analysis by gender indicated some evidence of elevated SBP in male participants, and the WMD (95% CI) was 1.49 mm Hg (1.03, 1.95). No meaningful effect on daytime office BP was detected in the present study, with evidence of significant heterogeneity. The follow-up time ranged from 15 weeks to a maximum of 7 years. Eight RCTs involving 36 806 participants were assessed. We further performed subgroup analysis and meta-regression by ethnicity, gender, age, health status, supplement dose, co-interventions, supplement duration and quality assessment. Cochrane Collaboration tool was used to assess the study quality of each trial. A random effects model was used to calculate the pooled weighted mean differences (WMDs) with 95% confidence intervals (CIs) for the continuous outcome data. The PubMed, the Embase and the Cochrane Central Register of controlled trials were searched. Thus, we conducted a meta-analysis of randomized controlled trials (RCTs) to explore the effect of calcium plus vitamin D (CaD) supplementation on changes of systolic blood pressure (SBP) and diastolic blood pressure among male and female participants (with and without diagnosed hypertension) aged 18 years or older. The combined efficacy of calcium and vitamin D on BP has not been systematically assessed. The effect of calcium or vitamin D supplement on blood pressure (BP) has been explored in previous meta-analyses, but the results are conflicting.
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The representative of the United Kingdom - Council President for July, speaking in her national capacity - stressed that these are “not just statistics” rather, they tell “the stories of real children and their families and communities”. In the ensuing all-day debate, more than 70 speakers voiced alarm over the scale of grave violations outlined in the Secretary-General’s report. “Peace doesn’t just happen when certain groups sign a piece of paper,” she said, stressing that a country that does not allow its youth and children to work towards building peace is “condemned to a future at war”. Despite the signing of a peace agreement, the conflict is still affecting communities in that country. “Due to recent escalations, we expect verified violations in at least some of these situations to increase over the coming months,” he warned.Īlso briefing the Council was Ms. Violeta, child civil society representative, who said that more than 3 million children and adolescents were victims to the conflict in Colombia due to recruitment, forced disappearance, kidnapping, displacement, murder and sexual violence. Omar Abdi, Deputy Executive Director at the United Nations Children’s Fund (UNICEF), pointed out that the highest numbers of grave violations against children were verified in protracted conflicts, including those in the Democratic Republic of the Congo, Israel, State of Palestine and Somalia. In Sudan, 1 million children have now been displaced by the fighting, and hundreds of children have been killed or injured. The United Nations is also engaging with parties to the conflicts in Ethiopia, Mozambique, Ukraine and the Russian Federation, she reported. In Iraq, the Government signed an action plan to prevent the recruitment of children by the Popular Mobilization Forces and repatriated 1,448 Iraqi children from north-east Syria. In 2022, 2,496 children were deprived of liberty for their actual or alleged association with parties to conflict.Īlso noting positive achievements, she spotlighted the situation in Yemen, where the United Nations signed an action plan with the Houthis to end and prevent violence. Further, instead of receiving protection, child victims are punished for their circumstances. Virginia Gamba, Special Representative of the Secretary-General for Children and Armed Conflict, told the 15-nation organ that the Secretary-General’s report on this topic (document A/77/895-S/2023/363) covers 27,800 violations against 18,890 children in 2022 - 8,630 killings or mutilations, 7,622 instances of recruitment and 3,985 abductions. Briefing the Security Council today, the senior official tasked with advocating for children in armed conflict noted that 2022 held the highest number of grave violations ever verified by the United Nations, with Government armed and security forces the main perpetrators of the killing and maiming of children, attacks on schools and hospitals, and denial of humanitarian access. Microsoft has made it easier than ever to include images, icons, and brand colors within your signature. It’s okay to get creative - some of these things can fit together on a single line of text. In general, aim to allow enough space for your name, job title, company, and phone number. Depending on what you include, you may have to make some choices about what information takes priority. In general, 3 – 4 lines of signature text should suffice. Here are a few things to keep in mind no matter how your signature ultimately takes shape. Regardless, your email signature should be a staple for all of your outgoing messages. In some cases, your company may also have brand guidelines or expectations for consistency across the organization. The design you ultimately choose will likely depend on your personal preferences. There are many ways to create an effective email signature. By including hyperlinks to social media profiles or helpful content, you can entice your recipient to engage with your brand and move them further down the sales funnel. Invite CommunicationĪn email signature can also serve as an invitation for your readers to learn more about your company. An email signature lets your readers know that you’re ready and willing to connect. Demonstrate ProfessionalismĮven the most basic signatures can elevate a first impression. If, like Unilever, you’re hoping to grow your social media following - or perhaps you’re running a special promotion or hoping to book more demo meetings - including the relevant information in your signature can help it stand out. Unilever had fantastic results with adding their Twitter link to their email signatures, increasing their following by nearly 500%. The heatmap studies above are a perfect example of this - if you want to draw attention to something in your email, you might want to consider making it a part of a well-designed signature. When crafted correctly, an effective Outlook signature can help achieve the following: Attract Attention Craft the perfect email Always have the best messaging at your fingertips Try Yesware Free The point here is that there is a right and a wrong way to plan and design your email signature - and the right way will generate a lot of opportunities for your business. Now, this isn’t to say that you absolutely must include a banner, or bright colors, or even any images at all. Look at that difference! The reader’s eyes are immediately drawn to the signature box, where they’re called to engage further with the brand. The following email was sent with an optimized and carefully crafted signature, with the CTA built-in. Worse than that, though, is the fact that the reader devotes almost no attention to the call-to-action underneath the signature. Notice the way the reader’s attention splits between the sender’s contact information and their company details - this information could certainly be better streamlined, to say nothing of its style or design. Let’s look at a couple of examples.īelow is the heatmap of an email with a basic (and somewhat poorly-designed) signature. In heat map studies, email signatures created with intentionality drew a tremendous amount of attention upon opening the email. It’s also an easy point of reference for anyone who needs to contact you. In many ways, it is akin to a digital business card for new contacts. Your email signature is, surprisingly, one of the best ways to make a first impression on your recipient.
Once you have created your world, you will be taken to the game where you can explore and start playing. This will bring you to the World Creation menu where you can create your world by selecting different options like world type, size, game mode, difficulty, and other add-ons.Ħ. To start playing the game, select ‘Create New’ from the game menu to build your world. Once version selection is completed, you’ll be taken to the game menu where you can create a new game or save and load from an existing game.ĥ. When the Minecraft game window opens, you will be given an option to choose between the Java Edition Version or the Bedrock Edition Version. You may need to accept EULA (End User License Agreement) before proceeding with the launch.ģ. Once the game has been purchased, downloaded and installed, launch it. Ensure that your device meets the minimum system requirements as outlined on the Minecraft website.Ģ. Purchase & Install the Minecraft Java Edition from the official Minecraft website. Launch Minecraft Java Edition with the following steps:ġ. You can also access the modding community from the Launcher, where you can browse and download mods to customize the game even further. Once you have selected Launcher, it will take you to the game launcher, which is where you can customize your game settings and choose which version of the game you would like to play.įrom the launcher, you can select which version you want to play, change game settings, and view/manage modpacks. To access it from the game menu, select Options and then select the Launcher option. The launcher in Minecraft can be found in the game menu. Once you have adjusted the settings to your liking, you can click ‘Save’ to save the changes and have them applied to the Launcher when you launch Minecraft. Clicking this button will open up a new window where you can configure various advanced settings for the Launcher, such as hardware acceleration, network settings, and authentication settings. On the left hand side of this screen, you will see a button labeled ‘Advanced Settings’. This will open up a list of all the different launch profiles that have been saved. Once the Launcher has been opened, you will need to click on the ‘Launch Options’ tab, located at the top of the window. In order to access the advanced settings on the Minecraft Launcher, you will need to first open the Launcher. |
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